α-Synuclein Sterically Stabilizes Spherical Nanoparticle-Supported Lipid Bilayers
نویسندگان
چکیده
منابع مشابه
α-Synuclein insertion into supported lipid bilayers as seen by in situ X-ray reflectivity.
Large aggregates of misfolded α-synuclein inside neuronal cells are the hallmarks of Parkinson's disease. The protein's natural function and its supposed toxicity, however, are believed to be closely related to its interaction with cell and vesicle membranes. Upon this interaction, the protein folds into an α-helical structure and intercalates into the membrane. In this study, we focus on the c...
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ژورنال
عنوان ژورنال: ACS Applied Bio Materials
سال: 2019
ISSN: 2576-6422,2576-6422
DOI: 10.1021/acsabm.8b00774